Hydroxypropyl Methyl Cellulose (HPMC)

Brief Description
CAS No.: 9004-65-3 Other Names: 2-hydroxypropyl Methyl ether MF: C3H7O
Place of Origin: Anhui China (Mainland) Type: Auxiliaries and Other Medicinal Chemicals Grade Standard: Cosmetic Grade, Food Grade, Med...
Brand Name: BBCA Pharm Purity: 99% appearance: white powder
Delivery Terms & Packaging
Packaging Detail:25kg/drum
Delivery Detail:7days
Specifications
Hydroxypropyl Methyl Cellulose (HPMC)

Name: Hydroxypropyl Methyl Cellulose
Abbreviation:HPMC\MHPC
CAS: 9004-65-3

Name: Hydroxypropyl Methyl Cellulose
Abbreviation:HPMC\MHPC
Alias: Cellulose, 2-hydroxypropyl Methyl ether.
CAS Registry Number: 9004-65-3
Sources:
The starting materials for manufacturing HPMC are selected from pure cotton cellulose. The synthetic process incorporates treatment of alkali cellulose with propylene oxide and methylene chloride in an organic solvent-water mixture. The whole process is automatic and monitored by machines. This product does not contain any additives, animal organs, lipids or oils.
Physical properties:
1. Appearance: HPMC is a nonionic cellulose ether, white grayish-white powder or granule,odorless and flavorless, soluble in cold water, glacial acetic acid, ethanol, methanol and propylene glycol, slightly soluble in acetone depending on the degree of substitutions, practically insoluble in hot water, ethylene glycol and toluene. HPMC is dissolved in a mixture of 10% methanol and 90% methylene chloride to form colloidal solutions.
2. The solution of HPMC has surface activity, high transparency, and stable performance. When heated at certain temperature, the solution becomes cloudy or forms flocculent gel. However, the solution becomes clear again after cooling. Different types of HPMC have different gelation temperatures. The solubility varies with the viscosity. The lower the viscosity, the higher solubility it has. The different types of HPMC are different in some properties and their solubility in water is not affected by pH.
3. Particle sizes:100% pass rate in 100 mesh
4. Apparent density: 0.25-0.70 g/mL (usually about 0.5 g/mL),specific density 1.26-1.31mL.
5. Color change temperature:190-200C; Carbonization temperature:280-300C.
6. The higher methoxyl content in HPMC, the lower gelation temperature, and the higher solubility in water and surface activity.
7. HPMC has some other characteristics, for example, thickening property, pH stability, retention of water, excellent film-forming property, good disperse and adhesion ability.
Applications:
1. Pharmaceutical aid:HPMC is used as adhesive, solutizer in tablet, film-forming reagents in pharmaceutical coating,delayed-release and controlled-release tablets or capsules, thickener and water-binding agent in liquid formulation, component in eye drop.
2. Food:HPMC is used as a component in adhesives, emulsifiers, stabilizing agents, water-binding agents, excipients and thickeners in various drinks, milks, spices and nutrition foods.
3. Cosmetic:HPMC is used as thickeners, adhesives, emulsifiers and film-forming reagents.
4. Industry: HPMC is used as the dispersing agents in the construction decoration, thickeners, adhesives and water-binding agents. HPMC is used as thickening agents, emulsifiers and stabilizers in the emulsion paints and the water soluble resin paints. HPMC is also used in the polyvinyl chloride preparation process as dispersing agents by the dispersion polymerization method.

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