chloroamphenicol; CAS RN.:56-75-7
| CAS No.: 56-75-7 | Other Names: 2,2-dichloro-n-[2-hydroxy-1-(hydro... | MF: C11H12Cl2N2O5 |
| EINECS No.: 200-287-4 | Place of Origin: Zhejiang China (Mainland) | Type: Antibiotic and Antimicrobial Agents |
| Grade Standard: Medicine Grade | Usage: Animal Pharmaceuticals | Brand Name: DERY |
| Model Number: DR-HM-001A | Purity: 99% |
| Packaging Detail: | 25kg/drum 25cm*25cm*36cm or customized packing when larger or smaller than 25kg |
| Delivery Detail: | In 15-20 days upon the receipt of the payment |
1. CAS RN.:56-75-7;
2. Spec.:USP33/EP6th/BP2010
3. the dominant products of our company;
4. high quality & competitive price;
Product Name:chloroamphenicol
Synonyms:
Standards: CP2010/USP33/EP6th/BP2010/IP2007
Chraracters
A white, greyish-white or yellowish-white, fine, crystalline powder or fine crystals, needles or elongated plates, slightly soluble in water, freely soluble in alcohol and in propylene glycol. A solution in ethanol is dextrorotatory and a solution in ethyl acetate is laevorotatory.
general info:Chloramphenicol is a bacteriocidal antimicrobial. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines.
General introduction:
Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use.In low-income countries, chloramphenicol is still widely used because it is exceedingly inexpensive and readily available.
Indications:
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
| Item | Standard | Result |
| Characters | Fine, white to grayish-white or yellowish white, needle-like crystals or elongated plates. | Qualified |
| Identification | IR | Qualified |
| HPLC | ||
| Melting range | 149°C~153°C | 149.0~151.5°C |
| Specific rotation | +18.5 ~ +20.0 | +19.60° |
| Crystallinity | Meets the requirements | Qualified |
| pH | 4.5-7.5 | 4.94 |
| Chromatographic purity | Individual impurity≤0.5%,Total impurities≤2% | Qualified |
| Residual solvents | Methanol≤0.3% | 0.00% |
| Methyl dichloroacetate≤0.5% | 0.00% | |
| Benzoic aldehyde≤0.5% | 0.00% | |
| Assay | 98.5-102.0 | 99.79% |
Storage:
kept in a light-proof,well-colsed,dry and cool place.